Detection and isolation of Mycoplasma fermentans from urine of human immunodeficiency virus type 1-infected patients Journal Article


Authors: Dawson, M. S.; Hayes, M. M.; Wang, R. Y. H.; Armstrong, D.; Kundsin, R. B.; Lo, S. C.
Article Title: Detection and isolation of Mycoplasma fermentans from urine of human immunodeficiency virus type 1-infected patients
Abstract: Mycoplasma fermentans (incognitus strain) has been linked with acquired immunodeficiency syndrome-associated nephropathy. Ten (23%) of 43 urine sediment specimens from 40 human immunodeficiency virus (HIV)-positive patients at different stages of acquired immunodeficiency syndrome disease tested positive in the polymerase chain reaction using a primer pair found in the insertion sequences specific to M fermentans. Mycoplasma fermentans was isolated from two HIV-positive patients' urine sediment specimens and on a repeated basis from one. All three culture-positive urine sediment specimens tested positive in the polymerase chain reaction. Fifty urine sediment specimens from age-matched HIV-negative healthy controls tested negative for M fermentans by polymerase chain reaction. Mycoplasma fermentans was not isolated from any of the control urine sediment specimens. Our results show a high prevalence of M fermentans in urine sediment specimens from HIV-positive patients but not from urine sediment specimens of HIV-negative healthy controls.
Keywords: dna; identification; disease; aids; infectious agent vlia; ureaplasma-urealyticum; incognitus
Journal Title: Archives of Pathology & Laboratory Medicine
Volume: 117
Issue: 5
ISSN: 0003-9985
Publisher: College of American Pathologists  
Date Published: 1993-05-01
Start Page: 511
End Page: 514
Language: English
ACCESSION: WOS:A1993LA78700014
PROVIDER: wos
PUBMED: 8489341
Notes: Article -- Source: Wos
Citation Impact
MSK Authors
  1. Donald Armstrong
    240 Armstrong