Prostate-specific antigen and prostate cancer: Prediction, detection and monitoring Journal Article
| Authors: | Lilja, H.; Ulmert, D.; Vickers, A. J. |
| Article Title: | Prostate-specific antigen and prostate cancer: Prediction, detection and monitoring |
| Abstract: | Testing for prostate-specific antigen (PSA) has profoundly affected the diagnosis and treatment of prostate cancer. PSA testing has enabled physicians to detect prostate tumours while they are still small, low-grade and localized. This very ability has, however, created controversy over whether we are now diagnosing and treating insignificant cancers. PSA testing has also transformed the monitoring of treatment response and detection of disease recurrence. Much current research is directed at establishing the most appropriate uses of PSA testing and at developing methods to improve on the conventional PSA test. © 2008 Nature Publishing Group. |
| Keywords: | treatment response; review; cancer risk; cancer radiotherapy; cancer diagnosis; prostate specific antigen; prediction; prostate cancer; prostate-specific antigen; prostatic neoplasms; early diagnosis; prostatectomy; finasteride; physician; prostate hypertrophy; cancer epidemiology; dutasteride; race difference; steroid 5alpha reductase inhibitor; antigen function |
| Journal Title: | Nature Reviews Cancer |
| Volume: | 8 |
| Issue: | 4 |
| ISSN: | 1474-175X |
| Publisher: | Nature Publishing Group |
| Date Published: | 2008-04-01 |
| Start Page: | 268 |
| End Page: | 278 |
| Language: | English |
| DOI: | 10.1038/nrc2351 |
| PUBMED: | 18337732 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 119" - "Export Date: 17 November 2011" - "CODEN: NRCAC" - "Source: Scopus" |
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