A critical assessment of the linear no-threshold hypothesis: Its validity and applicability for use in risk assessment and radiation protection Journal Article
| Authors: | Siegel, J. A.; Brooks, A. L.; Fisher, D. R.; Zanzonico, P. B.; Doss, M.; O'Connor, M. K.; Silberstein, E. B.; Welsh, J. S.; Greenspan, B. S. |
| Article Title: | A critical assessment of the linear no-threshold hypothesis: Its validity and applicability for use in risk assessment and radiation protection |
| Abstract: | The Society of Nuclear Medicine and Molecular Imaging convened a task group to examine the evidence for the risk of carcinogenesis from low-dose radiation exposure and to assess evidence in the scientific literature related to the overall validity of the linear no-threshold (LNT) hypothesis and its applicability for use in risk assessment and radiation protection. In the low-dose and dose-rate region, the group concluded that the LNT hypothesis is invalid as it is not supported by the available scientific evidence and, instead, is actually refuted by published epidemiology and radiation biology. The task group concluded that the evidence does not support the use of LNT either for risk assessment or radiation protection in the low-dose and dose-rate region. © 2019 Wolters Kluwer Health, Inc. All rights reserved. |
| Keywords: | controlled study; cancer risk; low drug dose; molecular imaging; risk assessment; validity; nuclear medicine; radiation carcinogenesis; radiation protection; scientific literature; radiobiology; article; alara; linear no-threshold; radiophobia |
| Journal Title: | Clinical Nuclear Medicine |
| Volume: | 44 |
| Issue: | 7 |
| ISSN: | 0363-9762 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2019-07-01 |
| Start Page: | 521 |
| End Page: | 525 |
| Language: | English |
| DOI: | 10.1097/rlu.0000000000002613 |
| PUBMED: | 31107746 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Source: Scopus |
