The controversial linear no-Threshold model Journal Article


Authors: Weber, W.; Zanzonico, P.
Article Title: The controversial linear no-Threshold model
Abstract: Estimating the risk of cancer induction by low-dose radiation (e.g., diagnostic) remains one of the most contentious issues in modern science and has engendered often-strident debate (1,2), particularly with respect to the linear no-Threshold (LNT) dose-response model. As John Boice, Jr., president of the National Council on Radiation Protection and Measurements (NCRP), has aptly stated (3), "LNT is not TNT, but differences in opinions sometimes appear explosive!" A critical assessment of the LNT model and a consideration of alternative dose-response models are presented in the article by Siegel, Pennington, and Sacks in this issue of The Journal of Nuclear Medicine (3). The article highlights the uncertainty associated with the LNT model and LNT model-based risk factors. © COPYRIGHT 2017 by the Society of Nuclear Medicine and Molecular Imaging.
Journal Title: Journal of Nuclear Medicine
Volume: 58
Issue: 1
ISSN: 0161-5505
Publisher: Society of Nuclear Medicine  
Date Published: 2017-01-01
Start Page: 7
End Page: 8
Language: English
DOI: 10.2967/jnumed.116.182667
PROVIDER: scopus
PUBMED: 27754908
DOI/URL:
Notes: Review -- Export Date: 2 February 2017 -- Source: Scopus
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  1. Pat B Zanzonico
    355 Zanzonico
  2. Wolfgang Andreas Weber
    173 Weber