| Abstract: |
A family of transcription factors, first identified as hepatocyte nuclear factors (HNF-3α, -3β, and -3γ) and as a homeotic Drosophila mutant, fork head, has been intensively studied for the past 4 years. Important findings have emerged about the structure of the DNA-binding portion of the proteins as well as biologic discoveries about the diversity of the family and its implied role in early development. |
| Keywords: |
dna-binding proteins; review; nonhuman; protein analysis; animal; gene expression; protein dna binding; transcription factor; transcription factors; nuclear proteins; crystallography, x-ray; protein structure, tertiary; liver cell; protein structure; protein family; x ray crystallography; nuclear factor; human; priority journal; support, non-u.s. gov't; support, u.s. gov't, p.h.s.
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