Changing patterns of infections in the immunocompromised patient with cancer Journal Article
| Authors: | Koll, B. S.; Brown, A. E. |
| Article Title: | Changing patterns of infections in the immunocompromised patient with cancer |
| Abstract: | Infectious complications have become frequent causes of morbidity and mortality in cancer patients, often replacing the primary disease as the leading cause of death. Intensive chemotherapy regimens, widespread prophylactic and therapeutic administration of antibiotics, and reliance on intravascular catheters have altered the epidemiology of infections in these patients. The authors review how gram-positive bacteremias have replaced gram-negative bacteremias as the leading causes of infections in many patients with cancer, and how fungal infections have become a leading cause of morbidity and mortality as bacterial infections are better controlled. Multiresistant organisms that have developed during the past decade and future trends in infectious complications of cancer patients are also discussed. |
| Keywords: | neutropenia; review; cancer patient; cytarabine; antineoplastic agent; neoplasms; infection; aciclovir; pneumocystis pneumonia; antibiotic resistance; ciprofloxacin; mycobacterium infections; virus infection; vancomycin; immune deficiency; immunocompromised host; corticosteroid; disease predisposition; mycobacterium; bacterial infection; bacterial infections; fluconazole; ganciclovir; candidiasis; mycosis; infection risk; virus diseases; mycobacteriosis; tuberculosis; triazole derivative; antimicrobial therapy; flucytosine; kanamycin; sulfamethoxazole; trimethoprim; cephalosporin derivative; gram positive bacterium; parasitosis; corticosteroid therapy; mycoses; amikacin; gram negative bacterium; clofazimine; isoniazid; amphotericin b; cycloserine; cancer; human; priority journal; cefoxitin; protozoan infections; ethionamide; aminosalicylic acid; genaconazole |
| Journal Title: | Hematology/Oncology Clinics of North America |
| Volume: | 7 |
| Issue: | 4 |
| ISSN: | 0889-8588 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1993-08-01 |
| Start Page: | 753 |
| End Page: | 769 |
| Language: | English |
| PUBMED: | 8354655 |
| PROVIDER: | scopus |
| DOI: | 10.1016/S0889-8588(18)30220-X |
| DOI/URL: | |
| Notes: | Source: Scopus |
