Sentinel node biopsy for melanocytic tumors in children Journal Article

  


Authors: Kayton, M. L.; La Quaglia, M. P.
Article Title: Sentinel node biopsy for melanocytic tumors in children
Abstract: Sentinel node biopsy is as pivotal for the staging of pediatric melanoma patients as it is for adults. However, pediatric patients frequently present the clinician with pigmented lesions-such as atypical Spitz tumors or Spitzoid melanomas-that are not easy to classify as benign or malignant, and often fall into a diagnostic gray area when assessed with light microscopy alone. For these lesions, the performance of sentinel node biopsy can contribute to an understanding of the lesion's biology. We present a strategy for incorporating sentinel node biopsy into the overall management approach to children with atypical pigmented lesions with features suspicious for melanoma. With the inclusion of additional adjunctive techniques such as comparative genomic hybridization, this algorithm may lend more diagnostic precision to difficult-to-classify lesions. © 2008 Elsevier Inc. All rights reserved.
Keywords: child; clinical feature; microscopy; anamnesis; interferon; cancer staging; positron emission tomography; lymph node metastasis; lymph node dissection; lymph nodes; lymphatic metastasis; lymphoscintigraphy; sentinel lymph node biopsy; melanoma; metastasis; computer assisted tomography; skin neoplasms; algorithms; pediatric; juvenile melanoma; physical examination; comparative genomic hybridization; sentinal lymph node; spitz tumor
Journal Title: Seminars in Diagnostic Pathology
Volume: 25
Issue: 2
ISSN: 0740-2570
Publisher: Elsevier Inc.  
Date Published: 2008-05-01
Start Page: 95
End Page: 99
Language: English
DOI: 10.1053/j.semdp.2008.05.001
PUBMED: 18697712
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-45849115863&partnerID=40&md5=cd9ad4b71b0ebb406e8f9e657e99c058
Notes: --- - "Cited By (since 1996): 7" - "Export Date: 17 November 2011" - "CODEN: SDPAE" - "Source: Scopus"
Altmetric
What is Altmetric?
Citation Impact
What is Dimensions Citation Badge?
BMJ Impact Analytics
MSK Authors
  1. Michael P La Quaglia
    411 La Quaglia
  2. Mark Lawrence Kayton
    19 Kayton
Related MSK Work