Lymphatic mapping in the management of melanoma in children Journal Article


Authors: Brady, M. S.; Weinberg, H.; Kraus, D.; Lewis, J. J.; Coit, D. G.; La Quaglia, M. P.; Busam, K.
Article Title: Lymphatic mapping in the management of melanoma in children
Abstract: Lymphatic mapping allows the surgeon to identify and remove the first draining (sentinel) lymph node from a primary melanoma with minimal morbidity. The procedure facilitates accurate staging and identification of patients in need of additional therapy. We used lymphatic mapping and sentinel lymph node biopsy in two children with melanoma. Both patients had evidence of metastatic melanoma in their sentinel lymph nodes and underwent regional lymphadenectomy. Malignant melanoma and atypical pigmented lesions in children remain diagnostically challenging for the pathologist and clinician. Misdiagnoses occur, and the correct interpretation of a melanocytic tumor is too often made only after recurrence or metastasis has occurred. The use of lymphatic mapping facilitates accurate staging and identifies children in whom additional therapy may be indicated. In addition, it can assist in the assessment of the biologic potential of a difficult lesion.
Keywords: adolescent; human tissue; case report; cancer staging; lymph node metastasis; lymph nodes; lymphatic metastasis; lymphoscintigraphy; melanoma; skin biopsy; skin neoplasms; skin cancer; biopsy; childhood cancer; lymphatic system; dye; lymph node biopsy; humans; human; male; priority journal; article
Journal Title: Pediatric Dermatology
Volume: 15
Issue: 6
ISSN: 0736-8046
Publisher: Blackwell Scientific Publications  
Date Published: 1998-11-01
Start Page: 421
End Page: 425
Language: English
DOI: 10.1046/j.1525-1470.1998.00999.x
PUBMED: 9875961
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 12 December 2016 -- Source: Scopus
Altmetric Score
MSK Authors
  1. Dennis Kraus
    258 Kraus
  2. Jonathan J Lewis
    107 Lewis
  3. Mary Sue Brady
    164 Brady
  4. Daniel Coit
    415 Coit
  5. Klaus J Busam
    536 Busam