ALK7 erects a suppressive barrier to tumor progression and metastasis Editorial

  


Authors: Li, X.; Ventura, A.
Title: ALK7 erects a suppressive barrier to tumor progression and metastasis
Abstract: Overcoming intrinsic and extrinsic tumor-suppressive barriers is an essential feature of tumor progression. In this issue of Developmental Cell, Michael et al. (2019)use the RIP-Tag mouse model to show that pro-apoptotic signals mediated by the Activin B-ALK7 axis suppress ectopic proliferation and metastasis during pancreatic neuroendocrine cancer development. © 2019 Elsevier Inc.
Keywords: controlled study; unclassified drug; nonhuman; animal cell; mouse; metastasis; animal experiment; animal model; carcinogenesis; cancer inhibition; transforming growth factor beta receptor; short survey; tumor growth; multiple cancer; pancreas islet cell tumor; priority journal; myelopid; transforming growth factor beta receptor alk7
Journal Title: Developmental Cell
Volume: 49
Issue: 3
ISSN: 1534-5807
Publisher: Cell Press  
Date Published: 2019-05-06
Start Page: 304
End Page: 305
Language: English
DOI: 10.1016/j.devcel.2019.04.025
PUBMED: 31063746
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064518883&doi=10.1016%2fj.devcel.2019.04.025&partnerID=40&md5=3482d08f293dc215c5f13710157d23d0
Notes: Short Survey -- Source: Scopus
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MSK Authors
  1. Andrea Ventura
    56 Ventura
  2. Xiaoyi Li
    5 Li
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