Nuclear imaging and minimally invasive surgery in the management of hyperparathyroidism Journal Article
| Authors: | Judson, B. L.; Shaha, A. R. |
| Article Title: | Nuclear imaging and minimally invasive surgery in the management of hyperparathyroidism |
| Abstract: | Primary hyperparathyroidism is the most common cause of hypercalcemia, and the treatment is primarily surgical. Because of biochemical screening, more patients now present with asymptomatic primary hyperparathyroidism, and consensus guidelines have been developed for the treatment of these patients. There is now considerable interest in minimally invasive approaches to the treatment of hyperparathyroidism. Sestamibi scanning as a localizing study, used in combination with anatomic imaging and intraoperative rapid parathyroid hormone assays, has enabled focused surgical approaches. Patients with localizing studies that indicate a single parathyroid adenoma are candidates for such approaches, including unilateral neck exploration, minimally invasive single-gland exploration, or endoscopic exploration instead of the traditional approach of bilateral neck exploration. Nuclear imaging is also critical to the successful management of patients with persistent or recurrent hyperparathyroidism. Copyright © 2008 by the Society of Nuclear Medicine, Inc. |
| Keywords: | treatment outcome; unclassified drug; review; pathophysiology; nuclear magnetic resonance imaging; computer assisted tomography; recurrence; calcium; calcium blood level; hypercalcemia; patient monitoring; practice guideline; diagnostic imaging; surgical approach; radiosurgery; endoscopic surgery; radiopharmaceutical agent; general anesthesia; methoxy isobutyl isonitrile technetium tc 99m; hyperparathyroidism; recurrent disease; parathyroid neoplasms; minimally invasive surgery; surgical procedures, minimally invasive; screening test; parathyroid adenoma; single photon emission computer tomography; parathyroid hormone; parathyroid hormone blood level; surgical anatomy; hormone determination; parathyroid carcinoma; parathyroidectomy; primary hyperparathyroidism; endocrinology; endoscopic exploration; minimally invasive single-gland exploration; parathyroid hormone assays; sestamibi; pertechnetic acid i 123; pertechnetic acid tc 99m; ectopic hormone production; parathyroid hormone release; parathyroid scintiscanning |
| Journal Title: | Journal of Nuclear Medicine |
| Volume: | 49 |
| Issue: | 11 |
| ISSN: | 0161-5505 |
| Publisher: | Society of Nuclear Medicine |
| Date Published: | 2008-11-01 |
| Start Page: | 1813 |
| End Page: | 1818 |
| Language: | English |
| DOI: | 10.2967/jnumed.107.050237 |
| PUBMED: | 18927330 |
| PROVIDER: | scopus |
| PMCID: | PMC3807731 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 10" - "Export Date: 17 November 2011" - "CODEN: JNMEA" - "Source: Scopus" |
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