Minimally invasive parathyroidectomy: The role of radio-guided surgery Journal Article


Authors: Shaha, A. R.; Patel, S. G.; Singh, B.
Article Title: Minimally invasive parathyroidectomy: The role of radio-guided surgery
Abstract: Objectives: Objectives were to review our current experience with radio-guided parathyroid surgery and to compare various techniques of minimally invasive parathyroidectomy. Study Design: 1) To review our recent experience of radio-guided gamma probe localization during surgery for primary hyperparathyroidism and 2) to compare the intraoperative findings with the preoperative sestamibi scan. Methods: Analysis was made of the 10 most recent surgical procedures for primary hyperparathyroidism at a single institution to compare the operative localization with preoperative sestamibi scan and to determine the radioactivity in the tissue removed during surgery, such as parathyroid adenoma, normal parathyroid gland, thyroid tissue, or lymph nodes. Results: The sestamibi scan was able to localize the enlarged parathyroid gland in eight patients. Although gamma probe was helpful in localizing the parathyroid gland, the identification of an enlarged parathyroid gland was directly based on the preoperative findings of sestamibi scan. In the remaining two patients, the intraoperative gamma probe was not helpful. Conclusions: The major advantage of gamma probe in the series was to evaluate the radioactivity in the tissue that was removed and to determine whether it was an enlarged parathyroid gland, lymph node, thyroid tissue, or fatty tissue. The radio-guided surgery did not add substantially to the surgical procedure in patients in whom the sestamibi scan had localized the enlarged parathyroid gland preoperatively.
Keywords: adult; clinical article; human tissue; aged; middle aged; surgical technique; radiopharmaceuticals; preoperative period; intraoperative period; lymph node; radioactivity; methoxy isobutyl isonitrile technetium tc 99m; hyperparathyroidism; intermethod comparison; minimally invasive surgery; surgical procedures, minimally invasive; thyroid gland; parathyroid adenoma; adipose tissue; technetium tc 99m sestamibi; parathyroid glands; gamma radiation; parathyroid surgery; parathyroidectomy; humans; human; male; female; priority journal; article; parathyroid localization; radio-guided surgery; sestamibi scan
Journal Title: Laryngoscope
Volume: 112
Issue: 12
ISSN: 0023-852X
Publisher: Wiley Blackwell  
Date Published: 2002-12-01
Start Page: 2166
End Page: 2169
Language: English
PUBMED: 12461334
PROVIDER: scopus
DOI: 10.1097/00005537-200212000-00007
DOI/URL:
Notes: Export Date: 14 November 2014 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Ashok R Shaha
    697 Shaha
  2. Bhuvanesh Singh
    242 Singh
  3. Snehal G Patel
    412 Patel