Signal transduction via the sphingomyelin pathway Journal Article


Authors: Kan, C. C.; Kolesnick, R.
Article Title: Signal transduction via the sphingomyelin pathway
Abstract: It has become evident that a recently defined sphingomyelin metabolic pathway can function in signal transduction. Ceramide, generated by sphingomyelin hydrolysis, plays a role as second messenger and stimulates a membranebound serine/threonine kinase termed ceramide-activated protein kinase. This pathway appears to mediate signal transduction for tumor necrosis factor-a. It is presumed that other cellsurface receptors may utilize this pathway for signalling. © 1993, FCCA(Forum: Carbohydrates Coming of Age). All rights reserved.
Keywords: signal transduction; sphingosine; ceramide; sphingomyelin pathway; ceramide-activated protein kinase
Journal Title: Trends in Glycoscience and Glycotechnology
Volume: 5
Issue: 22
ISSN: 0915-7352
Publisher: FCCA  
Date Published: 1993-03-01
Start Page: 99
End Page: 106
Language: English
DOI: 10.4052/tigg.5.99
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 1 March 2019 -- Source: Scopus
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  1. Richard N Kolesnick
    299 Kolesnick
  2. Chu-Cheng Kan
    8 Kan