The use of a multi-leaf collimator for conformal radiotherapy of carcinomas of the prostate and nasopharynx Journal Article

  


Authors: LoSasso, T.; Chui, C. S.; Kutcher, G. J.; Leibel, S. A.; Fuks, Z.; Ling, C. C.
Article Title: The use of a multi-leaf collimator for conformal radiotherapy of carcinomas of the prostate and nasopharynx
Abstract: We investigate the use of a multi-leaf collimator for conformal radiation therapy of carcinomas of the prostate and of the nasopharynx. Following verification of dose calculation algorithms for multi-leaf collimated fields using film dosimetry, we compute dose distributions for multi-field conformal treatment using fields shaped with either the multi-leaf collimator or conventional cerrobend blocks. We compare the two sets of treatment plans using graphical isodose displays, tissue specific dose volume histograms, tumor control probabilities, and normal tissue complication probabilities. We also incorporate setup errors into the calculated dose distributions to assess the effect of treatment uncertainties on the various criteria. Based on these comparisons, we conclude that for multi-field conformal radiotherapy for these two disease sites, the use of multi-leaf collimation is equivalent to that of conventional cerrobend blocks. © 1993.
Keywords: comparative study; radiation dose; nuclear magnetic resonance imaging; adenocarcinoma; computer assisted tomography; radiotherapy dosage; prostate cancer; prostatic neoplasms; prostate; algorithm; collimator; radiotherapy planning, computer-assisted; film dosimeter; image processing, computer-assisted; nasopharynx cancer; nasopharyngeal neoplasms; radiotherapy, high-energy; histogram; radiation scattering; nasopharynx; conformal radiotherapy; human; male; priority journal; article; support, u.s. gov't, p.h.s.; x ray dose distribution; multi-leaf collimation
Journal Title: International Journal of Radiation Oncology, Biology, Physics
Volume: 25
Issue: 2
ISSN: 0360-3016
Publisher: Elsevier Inc.  
Date Published: 1993-01-15
Start Page: 161
End Page: 170
Language: English
DOI: 10.1016/0360-3016(93)90337-u
PUBMED: 8420865
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027403894&doi=10.1016%2f0360-3016%2893%2990337-U&partnerID=40&md5=837e607eb9e7eaaa4841ea2703c61c6b
Notes: Article -- Export Date: 1 March 2019 -- Source: Scopus
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MSK Authors
  1. Zvi Fuks
    427 Fuks
  2. Steven A Leibel
    252 Leibel
  3. Gerald J Kutcher
    106 Kutcher
  4. C Clifton Ling
    331 Ling
  5. Thomas J LoSasso
    99 LoSasso
  6. Chen Chui
    144 Chui
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