Preclinical evaluation of the reliability of a 50 MeV racetrack microtron Journal Article


Authors: Masterson, M. E.; Mageras, G. S.; LoSasso, T.; Joreskog, E.; Larsson, L. G.; Tsirakis, B.; Febo, R.; Mohan, R.; Ling, C. C.; Leibel, S. A.; Fuks, Z.; Kutcher, G. J.
Article Title: Preclinical evaluation of the reliability of a 50 MeV racetrack microtron
Abstract: Purpose: A 50 MeV racetrack microtron has been installed and tested at Memorial Sloan-Kettering Cancer Center. It is designed to execute multi-segment conformal therapy automatically under computer control using scanned X ray and electron beams from 10 to 50 MeV. Prior to acceptance of the machine from the manufacturer, formal reliability testing was carried out. Only in this way could confidence be gained in its usefulness for routine 3D computer-controlled conformal therapy. Materials and Methods: To assess reliability, a set of 25 multi-segment test cases, each consisting of 10 to 17 fixed segments, was developed. The field arrangements and modalities for some of the test cases were identical to 3D conformal treatments that were being delivered with multiple static fields on conventional linear accelerators at our institution. Other cases were designed to explore reliability under more complex sets of conditions. These cases were "treated" repeatedly during a total period of 45 hours, over 5 days. During the treatments, ion chambers attached to the head of the machine provided dosimetric data for each field. Data from sensors connected to every set-up parameter (for example, couch positions, gantry angle, collimator leaf positions, etc.) were recorded and verified by an external computer. Results: While preliminary tests indicated an interlock rate of 5%, final reliability test results demonstrated an interlock fault rate of approximately 0.5%. The reproducibility of dosimetric data and geometric setup parameters was within specifications. As an example, leaf position reproducibility in the patient plane was within 0.5 mm for 97% of the setups. The times required to carry out treatments were recorded and compared with the times to carry out identical treatments on a conventional linear accelerator with cerrobend blocks. Areas where additional time savings can be achieved were identified. Conclusion: As an integral part of acceptance testing, the Scanditronix MM50 was rigorously tested for reliability. The machine successfully passed these tests, providing increased confidence in its usefulness for routine 3D conformal therapy. © 1994.
Keywords: nonhuman; neoplasms; reproducibility; radiotherapy dosage; radiotherapy; dosimetry; reliability; collimator; ionization chamber; x ray; computer analysis; electron beam; conformal radiotherapy; sensor; radiotherapy, computer-assisted; human; male; priority journal; article; support, u.s. gov't, p.h.s.; computer control; racetrack microtron; radiotherapy machine; roentgen apparatus
Journal Title: International Journal of Radiation Oncology, Biology, Physics
Volume: 28
Issue: 5
ISSN: 0360-3016
Publisher: Elsevier Inc.  
Date Published: 1994-03-30
Start Page: 1219
End Page: 1227
Language: English
DOI: 10.1016/0360-3016(94)90498-7
PROVIDER: scopus
PUBMED: 8175409
DOI/URL:
Notes: Export Date: 14 January 2019 -- Article -- Source: Scopus
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MSK Authors
  1. Zvi Fuks
    428 Fuks
  2. Steven A Leibel
    252 Leibel
  3. Gerald J Kutcher
    106 Kutcher
  4. Gikas S Mageras
    277 Mageras
  5. C Clifton Ling
    331 Ling
  6. Thomas J LoSasso
    99 LoSasso
  7. Robert   Febo
    10 Febo
  8. Radhe   Mohan
    97 Mohan