Role of lymph node dissection in renal cell cancer Journal Article

Authors: John, N. T.; Blum, K. A.; Hakimi, A. A.
Article Title: Role of lymph node dissection in renal cell cancer
Abstract: Lymph node metastasis in renal cell cancer (RCC) portends an extremely poor prognosis. Despite proven staging benefit, the therapeutic value of lymph node dissection in RCC remains questionable. The only prospective randomized trial examining its role failed to show any benefit. However, subsequent retrospective publications have attempted to identify high-risk cohorts and clinical scenarios where removal of nodes may improve survival. The aim of this article is to provide a comprehensive review looking at the role of lymph node dissection in RCC if any, the ideal extent of dissection, and also tools a clinician could employ to identify those who would most likely benefit from this exercise. © 2018 Elsevier Inc.
Keywords: survival; lymph node dissection; biomarkers; renal cell cancer; complications; prognosis
Journal Title: Urologic Oncology: Seminars and Original Investigations
Volume: 37
Issue: 3
ISSN: 1078-1439
Publisher: Elsevier Inc.  
Date Published: 2019-03-01
Start Page: 187
End Page: 192
Language: English
DOI: 10.1016/j.urolonc.2018.03.006
PROVIDER: scopus
PUBMED: 29602639
Notes: Source: Scopus
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MSK Authors
  1. Abraham Ari Hakimi
    152 Hakimi
  2. Kyle Blum
    13 Blum