Functional Magnetic Resonance Imaging in Prostate Cancer Journal Article
| Authors: | Seitz, M.; Shukla-Dave, A.; Bjartell, A.; Touijer, K.; Sciarra, A.; Bastian, P. J.; Stief, C.; Hricak, H.; Graser, A. |
| Article Title: | Functional Magnetic Resonance Imaging in Prostate Cancer |
| Abstract: | Context: Magnetic resonance imaging (MRI) combined with magnetic resonance spectroscopy imaging (MRSI), dynamic contrast-enhanced MRI, and diffusion-weighted MRI emerged as promising tests in the diagnosis of prostate cancer, and they show encouraging results. Objective: This review emphasizes different functional MRI techniques in the diagnosis of prostate cancer and includes information about their clinical value and usefulness. Evidence acquisition: The authors searched the Medline, Embase, and Cochrane Library databases. There were no language restrictions. The last search was performed in October 2008. Evidence synthesis: The combination of conventional MRI with functional MRI techniques is more reliable for differentiating benign and malignant prostate tissues than any other diagnostic procedure. At present, no guideline is available that outlines which technique is best in a specific clinical situation. It also remains uncertain whether improved spatial resolution and signal-to-noise ratio of 3-T MRI will improve diagnostic performance. Conclusions: A limited number of small studies suggest that functional MRI may improve the diagnosis and staging of prostate cancer. This finding needs further confirmation in larger studies, and cost-effectiveness needs to be established. © 2009 European Association of Urology. |
| Keywords: | review; cancer staging; magnetic resonance imaging; neoplasm recurrence, local; biopsy; prostate cancer; prostatic neoplasms; prostate; active surveillance; contrast enhancement; magnetic resonance spectroscopy; nuclear magnetic resonance spectroscopy; medline; cochrane library; functional magnetic resonance imaging; false negative reactions; diffusion weighted imaging; dynamic contrast-enhanced mri; functional mri; 1.5 tesla; 3 tesla; diffusion-weighted mri; metabolic imaging; embase |
| Journal Title: | European Urology |
| Volume: | 55 |
| Issue: | 4 |
| ISSN: | 0302-2838 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2009-04-01 |
| Start Page: | 801 |
| End Page: | 814 |
| Language: | English |
| DOI: | 10.1016/j.eururo.2009.01.027 |
| PUBMED: | 19185981 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 7" - "Export Date: 30 November 2010" - "CODEN: EUURA" - "Source: Scopus" |
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