Craniofacial and intracranial manifestations of langerhans cell histiocytosis: Report of findings in 100 patients Journal Article
| Authors: | D'Ambrosio, N.; Soohoo, S.; Warshall, C.; Johnson, A.; Karimi, S. |
| Article Title: | Craniofacial and intracranial manifestations of langerhans cell histiocytosis: Report of findings in 100 patients |
| Abstract: | OBJECTIVE. The purpose of this study was to review the craniofacial and intracranial clinical and radiologic manifestations of patients diagnosed with Langerhans cell histiocytosis (LCH). This report will compare the frequency of the various manifestations found in our series with those reported in the medical literature. CONCLUSION. In LCH, involvement of the calvaria, skull base, maxillofacial bones, and hypothalamic-pituitary axis is fairly common. The precise location of these lesions contributes to the variety of clinical manifestations of LCH, which includes scalp and/or facial swelling, seizures, hearing loss, recurrent otitis media, gingival bleeding, proptosis, diabetes insipidus, and cranial nerve palsies. © American Roentgen Ray Society. |
| Keywords: | adolescent; adult; child; child, preschool; retrospective studies; major clinical study; clinical feature; neuroimaging; magnetic resonance imaging; edema; computer assisted tomography; tomography, x-ray computed; hypothalamus hypophysis system; infant; brain diseases; medical literature; seizure; histiocytosis; skull base; radiodiagnosis; maxilla; cranial nerve paralysis; hearing loss; bone diseases; langerhans cell histiocytosis; otitis media; langerhans cell; exophthalmos; skull; face edema; craniofacial; intracranial; calvaria; diabetes insipidus; gingiva bleeding; histiocytosis, langerhans-cell |
| Journal Title: | American Journal of Roentgenology |
| Volume: | 191 |
| Issue: | 2 |
| ISSN: | 0361-803X |
| Publisher: | American Roentgen Ray Society |
| Date Published: | 2008-08-01 |
| Start Page: | 589 |
| End Page: | 597 |
| Language: | English |
| DOI: | 10.2214/ajr.07.3573 |
| PUBMED: | 18647937 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 8" - "Export Date: 17 November 2011" - "CODEN: AJROA" - "Source: Scopus" |
