Authors: | Dalal, K. M.; Antonescu, C. R.; Singer, S. |
Article Title: | Diagnosis and management of lipomatous tumors |
Abstract: | Lipomatous tumors range from benign lipomas to high-grade liposarcomas. Liposarcomas are classified into five histologic subtypes: well-differentiated, dedifferentiated, myxoid, round cell, and pleomorphic, which differ in outcomes and patterns of recurrence. Surgical resection is the mainstay of curative treatment; however, large, high grade liposarcomas may benefit from multimodality treatment with chemotherapy and radiation. A histologic-subtype specific nomogram provides accurate survival predictions. Prospective randomized clinical trials will continue to improve our care of patients with liposarcoma. © 2008 Wiley-Liss, Inc. |
Keywords: | cancer chemotherapy; cancer surgery; clinical feature; clinical trial; histopathology; review; cancer localization; cancer recurrence; doxorubicin; cancer radiotherapy; chemotherapy, adjuvant; combined modality therapy; treatment; cancer staging; molecular genetics; nuclear magnetic resonance imaging; follow up; cancer diagnosis; prospective study; computer assisted tomography; multiple cycle treatment; tumor biopsy; ifosfamide; postoperative complication; diagnosis; epirubicin; cancer epidemiology; external beam radiotherapy; recombinant granulocyte colony stimulating factor; management; wound complication; nomogram; liposarcoma; lipoma; hibernoma; lipoblastoma; lipoblastomatosis |
Journal Title: | Journal of Surgical Oncology |
Volume: | 97 |
Issue: | 4 |
ISSN: | 0022-4790 |
Publisher: | Wiley Blackwell |
Date Published: | 2008-03-15 |
Start Page: | 298 |
End Page: | 313 |
Language: | English |
DOI: | 10.1002/jso.20975 |
PUBMED: | 18286473 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 31" - "Export Date: 17 November 2011" - "CODEN: JSONA" - "Source: Scopus" |