Primary cutaneous myxoid melanoma: Immunohistologic clues to a difficult diagnosis Journal Article


Authors: Prieto, V. G.; Kanik, A.; Salob, S.; McNutt, N. S.
Article Title: Primary cutaneous myxoid melanoma: Immunohistologic clues to a difficult diagnosis
Abstract: We describe a 25-year-old man with a primary cutaneous myxoid malignant melanoma and xeroderma pigmentosum. Histologically, the tumor had a lentiginous intraepidermal component and a dermal myxoid nodule containing fusiform cells with hyperchromatic nuclei and nuclear pseudoinclusions. Immunohistochemically, the tumor cells were positive for S-100 protein in both the epidermis and the dermis and did not stain with HMB-45, AE1-AE3, MNF 116, antiactin, or anti-p53 protein. Although this tumor is rare, it should be considered in the differential diagnosis of cutaneous myxoid lesions.
Keywords: neoplasms; tumors; tissues; malignant-melanoma; immunoperoxidase; neurotized melanocytic nevi; neurofibromas
Journal Title: Journal of the American Academy of Dermatology
Volume: 30
Issue: 2 Pt. 2
ISSN: 0190-9622
Publisher: Mosby Elsevier  
Date Published: 1994-02-01
Start Page: 335
End Page: 339
Language: English
ACCESSION: WOS:A1994MV41300011
DOI: 10.1016/s0190-9622(94)70035-4
PROVIDER: wos
PUBMED: 8294593
Notes: Source: Wos
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