Authors: | Prieto, V. G.; Kanik, A.; Salob, S.; McNutt, N. S. |
Article Title: | Primary cutaneous myxoid melanoma: Immunohistologic clues to a difficult diagnosis |
Abstract: | We describe a 25-year-old man with a primary cutaneous myxoid malignant melanoma and xeroderma pigmentosum. Histologically, the tumor had a lentiginous intraepidermal component and a dermal myxoid nodule containing fusiform cells with hyperchromatic nuclei and nuclear pseudoinclusions. Immunohistochemically, the tumor cells were positive for S-100 protein in both the epidermis and the dermis and did not stain with HMB-45, AE1-AE3, MNF 116, antiactin, or anti-p53 protein. Although this tumor is rare, it should be considered in the differential diagnosis of cutaneous myxoid lesions. |
Keywords: | neoplasms; tumors; tissues; malignant-melanoma; immunoperoxidase; neurotized melanocytic nevi; neurofibromas |
Journal Title: | Journal of the American Academy of Dermatology |
Volume: | 30 |
Issue: | 2 Pt. 2 |
ISSN: | 0190-9622 |
Publisher: | Mosby Elsevier |
Date Published: | 1994-02-01 |
Start Page: | 335 |
End Page: | 339 |
Language: | English |
ACCESSION: | WOS:A1994MV41300011 |
DOI: | 10.1016/s0190-9622(94)70035-4 |
PROVIDER: | wos |
PUBMED: | 8294593 |
Notes: | Source: Wos |