Renal myxoma: A report of two cases and review of the literature Journal Article


Authors: Melamed, J.; Reuter, V. E.; Erlandson, R. A.; Rosai, J.
Article Title: Renal myxoma: A report of two cases and review of the literature
Abstract: Renal myxomas are rare neoplasms. Seven cases have been reported, of which only two are convincingly diagnosed as myxoma; the remaining cases exhibit features of sarcoma, fibroepithelial polyp, or myxolipoma. We report two additional cases; one in a 52-year-old man and another in a 68-year-old woman. They were discovered incidentally by radiological examination. The resected kidney in both patients contained a well-demarcated gelatinous intraparenchymal tumor, which consisted of occasional slender spindle cells scattered in an abundant myxoid stroma, closely resembling myxomas of other sites. The tumor cells showed immunoreactivity for vimentin but not for S- 100 protein, epithelial membrane antigen (EMA), CAM 5.2, HHF-35, or smooth muscle actin. Ultrastructural features were of fibroblast-like cells with an elaborate network of cytoplasmic processes. The differential diagnosis of myxoid tumors of the kidney includes myxoid variants of renal sarcomas and carcinomas, renomedullary interstitial cell tumors, and fibroepithelial polyps. It is important to recognize the existence of a renal myxoma, to avoid confusing this benign tumor with the malignant neoplasms with secondary myxoid features that may involve the kidney.
Keywords: immunohistochemistry; adult; human tissue; case report; differential diagnosis; kidney tumor; ultrastructure; myxoma; human; male; female; article
Journal Title: American Journal of Surgical Pathology
Volume: 18
Issue: 2
ISSN: 0147-5185
Publisher: Lippincott Williams & Wilkins  
Date Published: 1994-02-01
Start Page: 187
End Page: 194
Language: English
DOI: 10.1097/00000478-199402000-00008
PROVIDER: scopus
PUBMED: 8291657
DOI/URL:
Notes: Export Date: 14 January 2019 -- Article -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Juan Rosai
    181 Rosai
  2. Victor Reuter
    1228 Reuter
  3. Robert A Erlandson
    125 Erlandson
  4. Jonathan Melamed
    22 Melamed