Author: | Coit, D. G. |
Title: | Isolation limb perfusion for melanoma: Current trends and future directions |
Conference Title: | Perfusion 1993: State of the art and future perspectives |
Abstract: | The current review summarizes briefly the reported limitations of the literature on isolation limb perfusion for melanoma, as well as current clinical research in the use of this modality. The most intriguing advance has been the combination of the cytokine tumour necrosis factor with melphalan; this has yielded a consistent complete response rate of 90%. Not all responses remain durable, and the impact of this very effective combination but potentially toxic regimen on patient survival remains to be shown. Future challenges in the field are proposed. |
Keywords: | cisplatin; antineoplastic agents; conference paper; carboplatin; melanoma; melphalan; regional perfusion; extremities; tumor necrosis factor; perfusion; perfusion, regional; limb perfusion; regional therapy; human; priority journal |
Journal Title | Melanoma Research |
Volume: | 4 |
Issue: | Suppl. 1 |
Conference Dates: | 1993 Mar 30 |
Conference Location: | Venice, Italy |
ISBN: | 0960-8931 |
Publisher: | Lippincott Williams & Wilkins |
Date Published: | 1994-03-01 |
Start Page: | 57 |
End Page: | 60 |
Language: | English |
PUBMED: | 8038599 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Conference Paper -- Export Date: 14 January 2019 -- Source: Scopus |