Isolation limb perfusion for melanoma: Current trends and future directions Conference Paper


Author: Coit, D. G.
Title: Isolation limb perfusion for melanoma: Current trends and future directions
Conference Title: Perfusion 1993: State of the art and future perspectives
Abstract: The current review summarizes briefly the reported limitations of the literature on isolation limb perfusion for melanoma, as well as current clinical research in the use of this modality. The most intriguing advance has been the combination of the cytokine tumour necrosis factor with melphalan; this has yielded a consistent complete response rate of 90%. Not all responses remain durable, and the impact of this very effective combination but potentially toxic regimen on patient survival remains to be shown. Future challenges in the field are proposed.
Keywords: cisplatin; antineoplastic agents; conference paper; carboplatin; melanoma; melphalan; regional perfusion; extremities; tumor necrosis factor; perfusion; perfusion, regional; limb perfusion; regional therapy; human; priority journal
Journal Title Melanoma Research
Volume: 4
Issue: Suppl. 1
Conference Dates: 1993 Mar 30
Conference Location: Venice, Italy
ISBN: 0960-8931
Publisher: Lippincott Williams & Wilkins  
Date Published: 1994-03-01
Start Page: 57
End Page: 60
Language: English
PUBMED: 8038599
PROVIDER: scopus
DOI/URL:
Notes: Conference Paper -- Export Date: 14 January 2019 -- Source: Scopus
Citation Impact
MSK Authors
  1. Daniel Coit
    542 Coit