The TGF-β family and its composite receptors Journal Article


Authors: Massagué, J.; Attisano, L.; Wrana, J. L.
Article Title: The TGF-β family and its composite receptors
Abstract: In their search for regulators of animal growth and development, biologists have often come upon members of the transforming growth factor β(TGF-β) family and have realized that these are among the most versatile carriers of growth and differentiation signals. New evidence suggests that these factors signal through receptors with remarkable structures. Each receptor is a complex of two distantly related transmembrane serine/threonine kinases that are both essential for signalling. TGF-β and related factors have at their disposal a repertoire of such receptors, a feature that could account for their multifunctional nature. © 1994.
Keywords: signal transduction; review; transforming growth factor beta; protein serine threonine kinase; animalia; protein family; growth factor receptor; priority journal
Journal Title: Trends in Cell Biology
Volume: 4
Issue: 5
ISSN: 0962-8924
Publisher: Elsevier Inc.  
Date Published: 1994-05-01
Start Page: 172
End Page: 178
Language: English
DOI: 10.1016/0962-8924(94)90202-x
PROVIDER: scopus
PUBMED: 14731645
DOI/URL:
Notes: Review -- Export Date: 1 February 2019 -- Source: Scopus
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  1. Joan Massague
    388 Massague
  2. Jeff Wrana
    39 Wrana