Cryptococcosis Journal Article


Authors: White, M. H.; Armstrong, D.
Article Title: Cryptococcosis
Abstract: Cryptococcal disease is the most common life-threatening fungal infection in patients with AIDS. The most common manifestation, meningitis, has an indolent presentation that may lead to a delay in diagnosis. Although clinical trials have demonstrated efficacy with fluconazole in some patients, amphotericin B, with or without flucytosine, is the treatment of choice. Lifelong suppression of cryptococcal disease after initial therapy, however, is best achieved with fluconazole. Prognostic staging systems and primary prophylaxis of cryptococcal disease are also discussed.
Keywords: clinical feature; review; disease classification; nonhuman; human immunodeficiency virus infection; relapse; prophylaxis; fluconazole; hiv infections; itraconazole; oral drug administration; flucytosine; aids-related opportunistic infections; amphotericin b; fungal meningitis; cryptococcosis; cryptococcus neoformans; prognosis; human; meningitis, cryptococcal
Journal Title: Infectious Disease Clinics of North America
Volume: 8
Issue: 2
ISSN: 0891-5520
Publisher: W.B. Saunders Co.  
Date Published: 1994-06-01
Start Page: 383
End Page: 398
Language: English
PUBMED: 8089466
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 1 February 2019 -- Source: Scopus
Citation Impact
MSK Authors
  1. Mary H White
    43 White
  2. Donald Armstrong
    240 Armstrong