Mycobacterium haemophilum: An emerging pathogen Journal Article


Authors: Kiehn, T. E.; White, M.
Article Title: Mycobacterium haemophilum: An emerging pathogen
Abstract: Mycobacterium haemophilum is emerging as a pathogen of immunocompromised patients particularly those with AIDS and organ transplants. Infection has also occurred in healthy children. Adults usually present with cutaneous manifestations, septic arthritis or occasionally pneumonia. Children have perihilar, cervical or submandibular adenitis. The organism grows on mycobacterial media supplemented with ferric ammonium citrate or hemin, incubated at 30°C to 32°C, two to three weeks after inoculation. The most active antimicrobial agents in vitro are amikacin, ciprofloxacin, clarithromycin, rifabutin and rifampin. Development of resistance to the rifamycins has been demonstrated after patients were treated for several months with several antimycobacterial agents, including the rifamycins. Treatment for several months with at least two agents demonstrated to have low MICs for the organism has been shown to be effective. © 1994 Friedr. Vieweg & Sohn Verlagsgesellschaft mbH.
Keywords: review; drug efficacy; animal; culture medium; pneumonia; antiinfective agent; antibiotic resistance; ciprofloxacin; lymphadenitis; mycobacterium haemophilum; mycobacterium infections; temperature; acquired immune deficiency syndrome; clarithromycin; immune deficiency; bacterium culture; rifampicin; antibiotic sensitivity; mycobacteriosis; rifabutin; organ transplantation; hemin; minimum inhibitory concentration; amikacin; human; priority journal; ferric ammonium citrate; bacterial arthritis
Journal Title: European Journal of Clinical Microbiology and Infectious Diseases
Volume: 13
Issue: 11
ISSN: 0934-9723
Publisher: Springer  
Date Published: 1994-11-01
Start Page: 925
End Page: 931
Language: English
DOI: 10.1007/bf02111493
PUBMED: 7698118
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 1 February 2019 -- Source: Scopus
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  1. Mary H White
    44 White
  2. Timothy E Kiehn
    101 Kiehn