Molecular profiling in the diagnosis and treatment of high grade sarcomas Journal Article
| Author: | Antonescu, C. R. |
| Article Title: | Molecular profiling in the diagnosis and treatment of high grade sarcomas |
| Abstract: | High-density microarrays are used to measure in a comprehensive manner large-scale ("profile") gene expression patterns (when tumor RNA is tested) or gene copy number changes (when tumor genomic DNA is tested). Microarray-based studies are increasingly useful in addressing a wide variety of questions in sarcoma biology. This review includes a brief description of the microarray methodology and data analysis, followed by few examples of the recent applications of gene expression in the diagnosis, classification, and treatment of sarcomas. Copyright © Informa Healthcare USA, Inc. |
| Keywords: | conference paper; methodology; cancer diagnosis; cancer grading; cluster analysis; gene expression; gene expression profiling; validation study; cancer therapy; sarcoma; gene expression regulation, neoplastic; dna; microarray analysis; dna, neoplasm; data analysis; dna microarray; cancer classification; molecular biology; oligonucleotide; comparative genomic hybridization; rna, neoplasm; soft tissue neoplasms; complementary dna; microarray technology |
| Journal Title: | Ultrastructural Pathology |
| Volume: | 32 |
| Issue: | 2 |
| ISSN: | 0191-3123 |
| Publisher: | Informa Healthcare |
| Date Published: | 2008-01-01 |
| Start Page: | 37 |
| End Page: | 42 |
| Language: | English |
| DOI: | 10.1080/01913120801897174 |
| PUBMED: | 18446666 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 1" - "Export Date: 17 November 2011" - "CODEN: ULPAD" - "Source: Scopus" |
