Utility of lesion diameter in the clinical diagnosis of cutaneous melanoma Journal Article
| Authors: | Abbasi, N. R.; Yancovitz, M.; Gutkowicz-Krusin, D.; Panageas, K. S.; Mihm, M. C.; Googe, P.; King, R.; Prieto, V.; Osman, I.; Friedman, R. J.; Rigel, D. S.; Kopf, A. W.; Polsky, D. |
| Article Title: | Utility of lesion diameter in the clinical diagnosis of cutaneous melanoma |
| Abstract: | Objective: To determine the utility of the current diameter criterion of larger than 6 mm of the ABCDE acronym for the early diagnosis of cutaneous melanoma. Design: Cohort study. Setting: Dermatology hospital-based clinics and community practice offices. Patients: A total of 1323 patients undergoing skin biopsies of 1657 pigmented lesions suggestive of melanoma. Main Outcome Measure: The maximum lesion dimension (diameter) of each skin lesion was calculated before biopsy using a novel computerized skin imaging system. Results: Of 1657 biopsied lesions, 853 (51.5%) were 6 mm or smaller in diameter. Invasive melanomas were diagnosed in 13 of 853 lesions (1.5%) that were 6 mm or smaller in diameter and in 41 of 804 lesions (5.1%) that were larger than 6 mm in diameter. In situ melanomas were diagnosed in 22 of 853 lesions (2.6%) that were 6 mm or smaller in diameter and in 62 of 804 lesions (7.7%) that were larger than 6 mm in diameter. Conclusion: The diameter guideline of larger than 6mm provides a useful parameter for physicians and should continue to be used in combination with the A, B, C, and E criteria previously established in the selection of atypical lesions for skin biopsy. ©2008 American Medical Association. All rights reserved. |
| Keywords: | adult; controlled study; human tissue; aged; middle aged; major clinical study; cancer diagnosis; neoplasm staging; melanoma; cohort studies; dermoscopy; skin biopsy; skin neoplasms; diagnosis, differential; biopsy; cancer invasion; skin; imaging system; nevus, pigmented; early diagnosis; artificial intelligence; carcinoma in situ; cancer size; practice guidelines as topic; predictive value of tests; seborrheic keratosis; dysplastic nevus; image processing, computer-assisted; roc curve; diagnosis, computer-assisted; dysplastic nevus syndrome; keratosis |
| Journal Title: | Archives of Dermatology |
| Volume: | 144 |
| Issue: | 4 |
| ISSN: | 0003-987X |
| Publisher: | American Medical Association |
| Date Published: | 2008-04-01 |
| Start Page: | 469 |
| End Page: | 474 |
| Language: | English |
| DOI: | 10.1001/archderm.144.4.469 |
| PUBMED: | 18427040 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 11" - "Export Date: 17 November 2011" - "CODEN: ARDEA" - "Source: Scopus" |
