Authors: | Orci, L.; Perrelet, A.; Ravazzola, M.; Amherdt, M.; Rothman, J. E.; Schekman, R. |
Article Title: | Coatomer-rich endoplasmic reticulum |
Abstract: | We identify in normal cells the existence of two distinct sites of the transitional endoplasmic reticulum (ER), one housing the Sec23p protein complex (the classical transitional element), the other the coatomer protein complex (the coatomer-rich ER). Experimental conditions that reduce transport from the ER to the Golgi complex lead to the overexpression of this newly defined coatomer-rich ER. |
Keywords: | controlled study; nonhuman; proteins; animal cell; animal; cell structure; membrane proteins; intracellular transport; animalia; endoplasmic reticulum; membrane protein; rat; rats; adenosine triphosphate; protein subunit; rats, wistar; nitrogen; in vitro; golgi complex; membrane vesicle; clathrin; pancreas islet; islets of langerhans; golgi apparatus; rats, inbred strains; priority journal; article; support, non-u.s. gov't; models, structural; 2,4 dinitrophenol; citrinin; antimycin a; dinitrophenols |
Journal Title: | Proceedings of the National Academy of Sciences of the United States of America |
Volume: | 91 |
Issue: | 25 |
ISSN: | 0027-8424 |
Publisher: | National Academy of Sciences |
Date Published: | 1994-12-06 |
Start Page: | 11924 |
End Page: | 11928 |
Language: | English |
DOI: | 10.1073/pnas.91.25.11924 |
PROVIDER: | scopus |
PMCID: | PMC45348 |
PUBMED: | 7991558 |
DOI/URL: | |
Notes: | Export Date: 14 January 2019 -- Article -- CODEN: PNASA C2 -- Source: Scopus |