Current status of radioimmunodetection Journal Article
| Authors: | Larson, S. M.; Divgi, C.; Scott, A.; Daghighian, F.; Macapinlac, H.; Welt, S. |
| Article Title: | Current status of radioimmunodetection |
| Abstract: | Radioimmunodetection is a nuclear medicine technique that depends on in vivo detection of localization of antibodies and antibody forms carrying radioactivity for the purpose of diagnosis in patients with cancer. Current methods take advantage of tracers suitable for high resolution γ-camera imaging, such as 99mTc and 111In, for common tumors, such as colon and lung cancers. In addition, tracers such as 125I have been used for the intraoperative detection of metastatic deposits. These methods detect from 75 to 90% of metastatic deposits with high specificity, and typically contribute important diagnostic information, even in 25-40% of patients with occult disease. © 1994. |
| Keywords: | major clinical study; conference paper; technetium 99m; sensitivity and specificity; radiopharmaceuticals; neoplasms; metastasis; lung cancer; monoclonal antibody; indium radioisotopes; iodine 131; iodine radioisotopes; colon cancer; neoplasm metastasis; indium 111; clinical trials; organotechnetium compounds; tomography, emission-computed, single-photon; occult cancer; radioimmunodetection; immunoscintigraphy; cancer; human; male; female |
| Journal Title: | Nuclear Medicine and Biology |
| Volume: | 21 |
| Issue: | 5 |
| ISSN: | 0969-8051 |
| Publisher: | Elsevier Science Inc. |
| Date Published: | 1994-07-01 |
| Start Page: | 721 |
| End Page: | 729 |
| Language: | English |
| DOI: | 10.1016/0969-8051(94)90043-4 |
| PROVIDER: | scopus |
| PUBMED: | 9241648 |
| DOI/URL: | |
| Notes: | Export Date: 14 January 2019 -- Article -- CODEN: NMBIE C2 -- Source: Scopus |
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163Divgi -
106
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959Larson -
98
Welt -
37
Daghighian -
62Scott
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