Random effects models for combining results from controlled and uncontrolled studies in a meta-analysis Journal Article


Authors: Li, Z.; Begg, C. B.
Article Title: Random effects models for combining results from controlled and uncontrolled studies in a meta-analysis
Abstract: A random effects model is used to analyze meta-analyses containing both controlled and uncontrolled studies. A noniterative estimator of the treatment effect is derived using least squares, with the between-study variance substituted by an empirical Bayes estimator. The estimator is shown to be strongly consistent when the between-study variance is known, and the variance estimator is also shown to be strongly consistent. The estimator is shown to have desirable heuristic properties. © 1994 Taylor & Francis Group, LLC.
Keywords: consistent estimator; empirical bayes estimator
Journal Title: Journal of the American Statistical Association
Volume: 89
Issue: 428
ISSN: 0162-1459
Publisher: American Statistical Association  
Date Published: 1994-12-01
Start Page: 1523
End Page: 1527
Language: English
DOI: 10.1080/01621459.1994.10476892
PROVIDER: scopus
DOI/URL:
Notes: Also available with DOI: 10.2307/2291015 -- Export Date: 14 January 2019 -- Article -- Source: Scopus
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  1. Colin B Begg
    306 Begg