i(5p) and del(6q) are nonrandom abnormalities in carcinoma cervix uteri: Cytogenetics of two newly developed cell lines Journal Article
| Authors: | Mitra, A. B.; Rao, P. H.; Pratap, M. |
| Article Title: | i(5p) and del(6q) are nonrandom abnormalities in carcinoma cervix uteri: Cytogenetics of two newly developed cell lines |
| Abstract: | The karyotypes of two recently developed cell lines derived from squamous cell carcinomas of uterine cervix have been analyzed and are described here. Several clonal rearrangements were identified in both cell lines. Abnormalities common to these two cell lines were i(5)(p10) and del(6)(q15q26). The i(5p) was confirmed by use of whole chromosome 5 painting probe in fluorescence in situ hybridization. Based on these findings and review of published data on the cytogenetics of carcinoma of uterine cervix these two lesions are considered to be nonrandom abnormalities associated with this tumor. © 1994. |
| Keywords: | human cell; squamous cell carcinoma; carcinoma, squamous cell; in situ hybridization, fluorescence; cytogenetics; cancer cell culture; tumor cells, cultured; chromosome aberration; fluorescence in situ hybridization; chromosomes, human, pair 6; chromosome deletion; karyotype; karyotyping; chromosome 6q; uterine cervix carcinoma; chromosome 5p; chromosomes, human, pair 5; cervix neoplasms; chromosome insertion; human; female; priority journal; article; inversion (genetics) |
| Journal Title: | Cancer Genetics and Cytogenetics |
| Volume: | 76 |
| Issue: | 1 |
| ISSN: | 0165-4608 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 1994-08-01 |
| Start Page: | 56 |
| End Page: | 58 |
| Language: | English |
| DOI: | 10.1016/0165-4608(94)90072-8 |
| PROVIDER: | scopus |
| PUBMED: | 8076353 |
| DOI/URL: | |
| Notes: | Export Date: 14 January 2019 -- Article -- Source: Scopus |
