Abstract: |
The versatility of glycals both as glycosyl donors and as glycosyl acceptors is used in the synthesis of the Lewisy determinant. This and the oligosaccharide described in the following communication consist of a determinant, a carbohydrate spacer, and a group suitable for the conjugation to a carrier protein. The spacer present in these new glycoproteins minimizes the likelihood that the protein carrier will distort the recognition property of the determinant. Copyright © 1994 by VCH Verlagsgesellschaft mbH, Germany |