Non-operative management of rectal cancer: Understanding tumor biology Journal Article

   


Authors: Wei, I. H.; Garcia-Aguilar, J.
Article Title: Non-operative management of rectal cancer: Understanding tumor biology
Abstract: The management of locally-advanced rectal cancer involves a combination of chemotherapy, chemoradiation, and surgical resection to provide excellent local tumor control and overall survival. However, aspects of this multimodality approach are associated with significant morbidity and long-term sequelae. In addition, there is growing evidence that patients with a clinical complete response to chemotherapy and chemoradiation treatments may be safely offered initial non-operative management in a rigorous surveillance program. Weighed against the morbidity and significant sequelae of rectal resection, recognizing how to best optimize non-operative strategies without compromising oncologic outcomes is critical to our understanding and treatment of this disease. COPYRIGHT© 2018 EDIZIONI MINERVA MEDICA.
Keywords: drug therapy; rectal neoplasms; chemoradiotherapy
Journal Title: Minerva Chirurgica
Volume: 73
Issue: 6
ISSN: 0026-4733
Publisher: Edizioni Minerva Medica  
Date Published: 2018-12-01
Start Page: 601
End Page: 618
Language: English
DOI: 10.23736/s0026-4733.18.07743-x
PROVIDER: scopus
PMCID: PMC6252165
PUBMED: 29795066
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85057553917&doi=10.23736%2fS0026-4733.18.07743-X&partnerID=40&md5=c474506cd2da57029b7374bcd25281c0
Notes: Minerva Chir. -- Export Date: 2 January 2019 -- Review -- CODEN: MICHA C2 - 29795066 -- Source: Scopus
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MSK Authors
  1. Julio Garcia Aguilar
    347 Garcia Aguilar
  2. Iris Hsin - chu Wei
    64 Wei
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