Addressing the unintentional consequences of cancer therapy with novel integrative therapeutics Journal Article
| Authors: | Bao, T.; Peppone, L. J.; Robinson, P. |
| Article Title: | Addressing the unintentional consequences of cancer therapy with novel integrative therapeutics |
| Abstract: | There are 15.5 million cancer survivors in the United States because of, in part, improvements in therapy. As a result, there will be an increased burden of long- and late-term complications of cancer care, such as metabolic alterations. These metabolic changes will include alterations in bone resorption, obesity, hypercholesterolemia, and diabetes mellitus. The majority of cancer treatment-related toxicities have focused on endocrine therapy; however, chemotherapy and supportive medications, such as steroids, contribute to the development of these disorders. Because of the chronicity of these metabolic changes and their impact on morbidity, cancer risk, and outcomes as well other negative effects, including musculoskeletal pain and vasomotor symptoms, alternative strategies must be developed. These strategies should include nonpharmacologic approaches. Here, we summarize metabolic changes secondary to cancer care and integrative approaches to help alleviate therapy-associated toxicities. |
| Keywords: | multimodality cancer therapy; combined modality therapy; neoplasm; neoplasms; metabolism; pathology; androgen antagonists; glucocorticoid; metabolic syndrome x; osteoporosis; disease management; antiandrogen; antineoplastic agents, hormonal; hypogonadism; antineoplastic hormone agonists and antagonists; glucocorticoids; metabolic syndrome; complication; procedures; delivery of health care, integrated; integrated health care system; humans; human; metabolic encephalopathy; brain diseases, metabolic |
| Journal Title: | American Society of Clinical Oncology Educational Book |
| Volume: | 38 |
| ISSN: | 1548-8756 |
| Publisher: | American Society of Clinical Oncology |
| Date Published: | 2018-05-23 |
| Start Page: | 822 |
| End Page: | 828 |
| Language: | English |
| DOI: | 10.1200/edbk_201411 |
| PROVIDER: | scopus |
| PUBMED: | 30231327 |
| DOI/URL: | |
| Notes: | Am Soc Clin Oncol Educ Book -- Export Date: 2 January 2019 -- Review -- Source: Scopus C2 - 30231327 |
