Recognizing hereditary renal cancers through the microscope: A pathology update Journal Article
| Authors: | Peng, Y. C.; Chen, Y. B. |
| Article Title: | Recognizing hereditary renal cancers through the microscope: A pathology update |
| Abstract: | A heightened understanding of hereditary renal cancer syndromes and their molecular basis has led to an increased awareness and recognition of these renal neoplasms by pathologists. Because a diagnosis of hereditary renal cell carcinoma has a profound impact on the patient and family members, when and how to raise such a suspicion via pathologic assessment has become an important yet very challenging task. This review discusses key clinicopathologic, immunohistochemical, and genetic characteristics of hereditary renal cancer syndromes, and important differential diagnostic challenges, emphasizing recent pathologic and molecular advances. © 2018 Elsevier Inc. |
| Keywords: | hereditary leiomyomatosis renal cell carcinoma; von hippel-lindau; kidney cancer; tuberous sclerosis; familial; succinate dehydrogenase; birt-hogg-dubé; hereditary papillary |
| Journal Title: | Surgical Pathology Clinics |
| Volume: | 11 |
| Issue: | 4 |
| ISSN: | 1875-9181 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2018-12-01 |
| Start Page: | 725 |
| End Page: | 737 |
| Language: | English |
| DOI: | 10.1016/j.path.2018.07.010 |
| PUBMED: | 30447838 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 3 December 2018 -- Source: Scopus |
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