Authors: | Krebs, S.; Monti, S.; Seshan, S.; Fox, J.; Mannelli, L. |
Article Title: | IgG4-related kidney disease in a patient with history of breast cancer: Findings on (18)F-FDG PET/CT |
Abstract: | A 64-year-old African American woman with history of stage III breast carcinoma, 3 years after complete response to therapy, presents with progressive fatigue, increasing arthralgia, and unintentional weight loss of 15 lb in 3 months. An F-FDG PET demonstrated new diffuse FDG avidity of the renal parenchyma, new FDG-avid foci in pancreas and lungs, and new FDG-avid lymph nodes above and below the diaphragm. While a retroperitoneal lymph node biopsy was inconclusive, a kidney biopsy resulted in diagnosis of diffuse, severe, IgG4-related tubulointerstitial nephritis. Treatment with corticosteroid led to complete resolution of the symptoms and PET findings. |
Keywords: | middle aged; case report; radiopharmaceuticals; diagnosis, differential; differential diagnosis; diagnostic imaging; breast neoplasms; immunology; immunoglobulin g; breast tumor; fluorodeoxyglucose f 18; fluorodeoxyglucose f18; carcinoma; radiopharmaceutical agent; autoimmune diseases; autoimmune disease; nephritis; humans; human; female; positron emission tomography-computed tomography; positron emission tomography computed tomography |
Journal Title: | Clinical Nuclear Medicine |
Volume: | 41 |
Issue: | 8 |
ISSN: | 0363-9762 |
Publisher: | Lippincott Williams & Wilkins |
Date Published: | 2016-08-01 |
Start Page: | e388 |
End Page: | e389 |
Language: | English |
DOI: | 10.1097/rlu.0000000000001252 |
PUBMED: | 27187735 |
PROVIDER: | scopus |
PMCID: | PMC4977093 |
DOI/URL: | |
Notes: | Article -- Export Date: 3 December 2018 -- Source: Scopus |