Diagnostic applications of nuclear medicine: Uterine cancers Book Section


Authors: Pandit-Taskar, N.; Mahajan, S.; Ma, W.
Editors: Strauss, H. W.; Mariani, G.; Volterrani, D.; Larson, S. M.
Article/Chapter Title: Diagnostic applications of nuclear medicine: Uterine cancers
Abstract: Cervical and uterine malignancies are a significant health issue for women worldwide. Uterine cancers are the most common gynecological cancers, although ovarian cancers have the highest mortality. The primary modalities for anatomic imaging are ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI). These imaging tools are used for the diagnosis, staging, and posttherapy follow-up for detection of recurrent disease; however, they lack biologic information. Positron emission tomography (PET) with [18F] fluoro-2-deoxy-D-glucose ([18F]FDG) imaging plays a critical role in the evaluation of cervical and uterine malignancies. A number of studies have established the role of [18F]FDG PET in the staging and prognosis of advanced cervical cancer. PET/MRI scanners with newer technology are available and in future may be the mainstay in assessment of gynecologic malignancies. Radionuclide lymphoscintigraphy is an established technique for sentinel lymph node (SNL) mapping in vulvar cancer. For cervical and endometrial cancer, it can help prevent morbidities that follow lymphadenectomies and there is convincing evidence that SLN mapping can be useful in early-stage disease. In this chapter, we discuss the role of nuclear imaging, especially [18F]FDG PET scanning, and summarize the initial experiences with PET/MRI in cervical and uterine cancers; we also discuss the use of lymphoscintigraphy in gynecological cancers. © Springer International Publishing Switzerland 2017. All rights reserved.
Keywords: endometrial cancer; lymphoscintigraphy; fdg pet/ct; cervical cancer
Book Title: Nuclear Oncology: From Pathophysiology to Clinical Applications. 2nd ed
Volume: 2
ISBN: 978-3-319-26234-5
Publisher: Springer  
Publication Place: Cham, Switzerland
Date Published: 2017-01-01
Start Page: 979
End Page: 1020
Language: English
DOI: 10.1007/978-3-319-26236-9_45
PROVIDER: scopus
DOI/URL:
Notes: Book Chapter: 35 -- Export Date: 3 December 2018 -- Source: Scopus
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  1. Weining Ma
    40 Ma
  2. Sonia Mahajan
    20 Mahajan
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