Chemical explorations driven by an enchantment with mitomycinoids - a 20-year account Journal Article
| Authors: | Danishefsky, S. J.; Schkeryantz, J. M. |
| Article Title: | Chemical explorations driven by an enchantment with mitomycinoids - a 20-year account |
| Abstract: | The mitomycins and mitomycinoids have attracted considerable attention from chemists and biochemists ever since their discovery over twenty years ago. This account highlights the more important discoveries, as well as tribulations, that occurred in our group en route toward the synthesis of these important antitumor compounds. |
| Keywords: | mitomycin c; derivatives; route; reduction; antibiotic; efficient; antitumor; congeners; dna cross-linking; nitroso-compounds; fr-900482; mitomycinoid; mitomycin k; leucomitomycin; aziridinomitosene; activation cascade; isomitomycin-a; mitosene |
| Journal Title: | Synlett |
| Volume: | 1995 |
| Issue: | Suppl. 1 |
| ISSN: | 0936-5214 |
| Publisher: | Georg Thieme Verlag Kg |
| Date Published: | 1995-05-01 |
| Start Page: | 475 |
| End Page: | 490 |
| Language: | English |
| ACCESSION: | WOS:A1995RD26100003 |
| PROVIDER: | wos |
| DOI: | 10.1055/s-1995-5299 |
| Notes: | Article -- SI -- Source: Wos |
