Mycobacterium haemophilum infections in bone marrow transplant recipients Journal Article


Authors: White, M. H.; Papadopoulos, E. B.; Small, T. N.; Kiehn, T. E.; Armstrong, D.
Article Title: Mycobacterium haemophilum infections in bone marrow transplant recipients
Abstract: The purpose of this study was to describe the clinical presentation, treatment, and outcome of Mycobacterium haemophilum infection in patients undergoing bone marrow transplantation at a cancer center. Bone marrow transplant recipients with M haemophilum infection were identified upon culture of the organism by implementing the organism’s unique requirements for growth. This report of the patients’ clinical and immunologic course is based on a retrospective chart review. Two distinctly different presentations of M haemophilum infection were observed. Three patients presented with cutaneous lesions, typical of those seen in previous reports of the infection. Two others developed pulmonary disease only. All patients received directed therapy against M haemophilum, but respiratory failure developed in the patients with pneumonia and they died. The remaining 3 patients survived and are free of infection. These are the only reported cases of M haemophilum infection in bone marrow transplant recipients. Early diagnosis obtained through biopsy and special request for culture conditions conducive to the growth of the organism may decrease morbidity and mortality, particularly in patients with pulmonary disease. © 1995 by Williams and Wilkins.
Keywords: adult; clinical article; survival rate; retrospective studies; acute granulocytic leukemia; clinical feature; lung disease; retrospective study; pneumonia; postoperative complication; postoperative complications; myelodysplastic syndrome; acute myeloblastic leukemia; surgical mortality; mycobacterium haemophilum; mycobacterium infections; bone marrow transplantation; aplastic anemia; respiratory failure; recipient; human; male; female; priority journal; article; support, u.s. gov't, p.h.s.
Journal Title: Transplantation
Volume: 60
Issue: 9
ISSN: 0041-1337
Publisher: Lippincott Williams & Wilkins  
Date Published: 1995-11-15
Start Page: 957
End Page: 960
Language: English
DOI: 10.1097/00007890-199511150-00013
PUBMED: 7491700
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 28 August 2018 -- Source: Scopus
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MSK Authors
  1. Trudy Small
    234 Small
  2. Mary H White
    43 White
  3. Timothy E Kiehn
    100 Kiehn
  4. Donald Armstrong
    240 Armstrong