Abstract: |
Nuclear medicine is the specialty of medical imaging which utilizes a variety of radionuclides incorporated into specific compounds for diagnostic imaging and therapeutic applications. During recent years research in this discipline has concentrated on the decay characteristics of particular radionuclides as well as upon the design of unique radiolabeled tracers necessary to achieve the time-dependent molecular image. Many of the radionuclides under consideration are accelerator produced. The cyclotron at Memorial Sloan-Kettering Cancer Center (MSKCC), one of the earliest accelerators dedicated to serve a medical research program, has undergone an extensive reconditioning effort to meet the challenges of enhanced operational performance and improved radiochemical production necessitated by the Center's clinical research effort. Special emphasis has been applied to the development of target systems in order to achieve pilot production of sufficient quantities of required radionuclides to undertake clinical evaluation of promising tracers. © 1995. |