Image registration of SPECT and CT images using an external fiduciary band and three-dimensional surface fitting in metastatic thyroid cancer Journal Article


Authors: Scott, A. M.; Macapinlac, H.; Zhang, J.; Daghighian, F.; Montemayor, N.; Kalaigian, H.; Sgouros, G.; Graham, M. C.; Kolbert, K.; Yeh, S. D. J.; Lai, E.; Goldsmith, S. J.; Larson, S. M.
Article Title: Image registration of SPECT and CT images using an external fiduciary band and three-dimensional surface fitting in metastatic thyroid cancer
Abstract: Image registration of 131I SPECT with CT scans was performed in a patient with metastatic thyroid carcinoma using an external fiduciary band and a three-dimensional surface-fitting algorithm. Areas of metastatic disease taking up 131I were accurately localized to the liver, lungs and vertebral bodies; providing information that could not be obtained by planar or SPECT images alone. Based on these findings, further invasive diagnostic procedures were not performed, therefore considerably altering management in this patient. This approach to image registration has immediate clinical utility in the registration and interpretation of SPECT studies with corresponding CT or MRI scans.
Keywords: adult; case report; liver neoplasms; bone metastasis; nuclear magnetic resonance imaging; diagnostic accuracy; tumor localization; computer assisted tomography; image interpretation, computer-assisted; lung neoplasms; tomography, x-ray computed; algorithms; liver metastasis; lung metastasis; spinal neoplasms; thyroid cancer; thyroid neoplasms; single photon emission computer tomography; image registration; carcinoma, papillary, follicular; tomography, emission-computed, single-photon; middle age; human; female; priority journal; article; support, non-u.s. gov't; support, u.s. gov't, non-p.h.s.; external fiduciary band; three-dimensional surface fitting
Journal Title: Journal of Nuclear Medicine
Volume: 36
Issue: 1
ISSN: 0161-5505
Publisher: Society of Nuclear Medicine  
Date Published: 1995-01-01
Start Page: 100
End Page: 103
Language: English
PUBMED: 7799059
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 28 August 2018 -- Source: Scopus
Citation Impact
MSK Authors
  1. George Sgouros
    146 Sgouros
  2. Samuel D J Yeh
    107 Yeh
  3. Eseng Lai
    45 Lai
  4. Katherine S Kolbert
    28 Kolbert
  5. Steven M Larson
    958 Larson
  6. Martin C Graham
    53 Graham
  7. Jiaju   Zhang
    34 Zhang
  8. Andrew M. Scott
    62 Scott