Assignment of the 36.5-kDa (RFC5), 37-kDa (RFC4), 38-kDa (RFC3), and 40-kDa (RFC2) subunit genes of human replication factor C to chromosome bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q11.23 Journal Article

  


Authors: Okumura, K.; Nogami, M.; Taguchi, H.; Dean, F. B.; Chen, M.; Pan, Z. Q.; Hurwitz, J.; Shiratori, A.; Murakami, Y.; Ozawa, K.; Eki, T.
Article Title: Assignment of the 36.5-kDa (RFC5), 37-kDa (RFC4), 38-kDa (RFC3), and 40-kDa (RFC2) subunit genes of human replication factor C to chromosome bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q11.23
Abstract: Replication factor C is a multimeric primer-recognition protein consisting of five subunits (p145, p40, p38, p37, and p36.5) and is essential for the processive elongation of DNA chains catalyzed by DNA polymerase δ or ε{lunate} in human cells. We have mapped the locations on human chromosomes of the genes coding for the four smaller subunits [p36.5 (RFC5), p37 (RFC4), p38 (RFC3), and p40 (RFC2)] using both PCR amplification from DNAs of a panel of somatic hybrids and fluorescence in situ hybridization to bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q11.23, respectively. © 1995.
Keywords: human cell; dna-binding proteins; dna polymerase; dna replication; polymerase chain reaction; in situ hybridization, fluorescence; cloning, molecular; gene mapping; fluorescence in situ hybridization; molecular sequence data; base sequence; dna primers; lymphocytes; genetic code; chromosome 12q; chromosome 3q; chromosome 7q; chromosome mapping; chromosomes, human, pair 3; gene replication; dna-directed dna polymerase; chromosome 13q; chromosomes, human, pair 13; hybrid cell; chromosome banding; chromosomes, human, pair 12; chromosomes, human, pair 7; chromosome band; dna polymerase iii; dna polymerase ii; genomic library; human; priority journal; article; support, non-u.s. gov't; macromolecular systems; gene assignment; sequence tagged sites
Journal Title: Genomics
Volume: 25
Issue: 1
ISSN: 0888-7543
Publisher: Elsevier Inc.  
Date Published: 1995-01-01
Start Page: 274
End Page: 278
Language: English
DOI: 10.1016/0888-7543(95)80135-9
PUBMED: 7774928
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028919274&doi=10.1016%2f0888-7543%2895%2980135-9&partnerID=40&md5=fa88dfd1c9d0bd6a00f18f92ee4ddb3f
Notes: Article -- Export Date: 28 August 2018 -- Source: Scopus
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MSK Authors
  1. Jerard Hurwitz
    206 Hurwitz
  2. Frank B. Dean
    23 Dean
  3. Zhen-Qiang Pan
    15 Pan
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