Resection of brain metastases from sarcoma Journal Article
| Authors: | Wroński, M.; Arbit, E.; Burt, M.; Perino, G.; Galicich, J. H.; Brennan, M. F. |
| Article Title: | Resection of brain metastases from sarcoma |
| Abstract: | Background: Brain metastases from sarcoma are rare, and data concerning the treatment and results of therapy are sparse. Methods: We retrospectively reviewed 25 patients with brain metastases from sarcoma of skeletal or soft-tissue origin, surgically treated in a single institution during 20 years. Results: In 18 patients the brain lesion was located supratentorially, and in 7 patients infratentorially. Median age at brain metastasis diagnosis was 25 years. Median time from primary diagnosis to diagnosis of brain metastasis was 26.7 months. Lung metastases were present in 19 patients and in 8 patients they were synchronous with the brain lesion. Pulmonary metastases were resected in 12 patients (48% of total, and 63% of those with pulmonary lesions). The overall median survival from diagnosis of the primary sarcoma was 38 months and from craniotomy was 7 months. The presence or absence of lung lesions did not alter the median survival as calculated from diagnosis of brain metastasis. Overall percent survival was 40% at 1 year and 16% at 2 years. Conclusions: Because brain metastases from sarcoma are refractory to alternative treatment, surgical excision is indicated when feasible. Brain metastases from sarcoma are uncommon, usually occurring with or after lung metastasis. Long-term survival is possible in some patients. © 1995 The Society of Surgical Oncology, Inc. |
| Keywords: | adolescent; adult; child; preschool child; aged; child, preschool; middle aged; survival rate; retrospective studies; mortality; multimodality cancer therapy; combined modality therapy; brain tumor; follow up; brain neoplasms; follow-up studies; metastasis; lung neoplasms; retrospective study; sarcoma; lung tumor; brain metastasis; humans; human; male; female; article |
| Journal Title: | Annals of Surgical Oncology |
| Volume: | 2 |
| Issue: | 5 |
| ISSN: | 1068-9265 |
| Publisher: | Springer |
| Date Published: | 1995-09-01 |
| Start Page: | 392 |
| End Page: | 399 |
| Language: | English |
| DOI: | 10.1007/bf02306371 |
| PUBMED: | 7496833 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 28 August 2018 -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work