Authors: | Shair, M. D.; Yoon, T. Y.; Danishefsky, S. J. |
Article Title: | Total synthesis of (±)‐dynemicin A |
Abstract: | Pivotal steps in the total synthesis of the enediyne antibiotic dynemicin A are (1) a palladium‐mediated double cross‐coupling reaction to construct the enediyne array, and (2) cycloaddition of a quinone imine with the anion of a suitably protected homophthalic anhydride followed by oxidation in air to fashion the anthraquinone moiety. (Figure Presented.) Copyright © 1995 by VCH Verlagsgesellschaft mbH, Germany |
Keywords: | total syntheses; anthraquinones; enediynes; dynemicin a |
Journal Title: | Angewandte Chemie: International Edition in English |
Volume: | 34 |
Issue: | 16 |
ISSN: | 0570-0833 |
Publisher: | Wiley - V C H Verlag GmbH & Co. KGaA |
Date Published: | 1995-09-01 |
Start Page: | 1721 |
End Page: | 1723 |
Language: | English |
DOI: | 10.1002/anie.199517211 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Article -- Export Date: 28 August 2018 -- Source: Scopus |