Progress on lamellarins Journal Article
| Authors: | Pla, D.; Albericio, F.; Alvarez, M. |
| Article Title: | Progress on lamellarins |
| Abstract: | This review covers recent literature on the lamellarins, a family of marine natural products, and related analogs, encompassing synthetic strategies for total synthesis, structure-activity relationships (SAR), and studies on mechanisms of biological action, namely in the context of anti-tumor activity. It reviews work published from January 2008 to December 2010. © 2011 The Royal Society of Chemistry. |
| Keywords: | unclassified drug; nonhuman; drug targeting; antineoplastic agent; apoptosis; enzyme inhibition; antineoplastic activity; cancer cell culture; drug potency; drug structure; drug screening; drug synthesis; structure activity relation; drug research; drug mechanism; drug cytotoxicity; pharmacophore; natural product; ic 50; nuclear localization signal; aspartic acid; reaction analysis; macrogol; chemical reaction; amino acid transport; dna topoisomerase; cross coupling reaction; mitochondrial respiration; azalamellarin d; dehydrolamellarin j; lamellarin d; lamellarin derivative; lamellarin epsilon; lamellarin m; lamellarin n; lamellarin x; malic acid |
| Journal Title: | MedChemComm |
| Volume: | 2 |
| Issue: | 8 |
| ISSN: | 2040-2503 |
| Publisher: | Royal Society of Chemistry |
| Date Published: | 2011-01-01 |
| Start Page: | 689 |
| End Page: | 697 |
| Language: | English |
| DOI: | 10.1039/c1md00003a |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Export Date: 3 October 2011" - "Source: Scopus" |
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