Metastatic complications of cancer involving the central and peripheral nervous systems Journal Article
| Authors: | Mendez, J. S.; DeAngelis, L. M. |
| Article Title: | Metastatic complications of cancer involving the central and peripheral nervous systems |
| Abstract: | Neurologic complications of cancer may involve both the central nervous system and peripheral nervous system manifesting as brain, leptomeningeal, intramedullary, intradural, epidural, plexus, and skull base metastases. Excluding brain involvement, neurologic complications affecting these other sites are relatively infrequent, but collectively they affect more than 25% of patients with metastatic cancer causing significant morbidity and mortality. Early diagnosis and intervention optimize quality of life and improve survival. © 2018 Elsevier Inc. |
| Keywords: | cancer chemotherapy; cancer surgery; clinical feature; review; erlotinib; bone metastasis; cancer radiotherapy; cytarabine; methotrexate; neuroimaging; nuclear magnetic resonance imaging; neurosurgery; cancer diagnosis; cancer palliative therapy; ipilimumab; cancer immunotherapy; dexamethasone; melphalan; steroid; thiotepa; carcinogenesis; cancer hormone therapy; spinal cord compression; brain metastasis; glucocorticoid; cerebrospinal fluid analysis; spine metastasis; meningeal metastasis; intracranial dural metastasis; spine surgery; cns; molecularly targeted therapy; epidural cord compression; leptomeningeal; neurologic complications; vemurafenib; cancer prognosis; dabrafenib; afatinib; nivolumab; cancer; human; priority journal; alectinib; pns; skull base and nerve plexuses; brachial plexus metastasis; intramedullary metastasis; lumbosacral plexus metastasis |
| Journal Title: | Neurologic Clinics |
| Volume: | 36 |
| Issue: | 3 |
| ISSN: | 0733-8619 |
| Publisher: | W.B. Saunders Co-Elsevier Inc. |
| Date Published: | 2018-08-01 |
| Start Page: | 579 |
| End Page: | 598 |
| Language: | English |
| DOI: | 10.1016/j.ncl.2018.04.011 |
| PROVIDER: | scopus |
| PMCID: | PMC6082424 |
| PUBMED: | 30072072 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 4 September 2018 -- Source: Scopus |
