When is contralateral mastectomy warranted in unilateral breast cancer? Journal Article
| Authors: | Barry, M.; Sacchini, V. |
| Article Title: | When is contralateral mastectomy warranted in unilateral breast cancer? |
| Abstract: | Contralateral mastectomy, in the setting of unilateral breast cancer, may only offer a survival benefit in selected patients. In fact, most women with a unilateral breast cancer will never develop a contralateral breast cancer. Despite this, there is a rapidly increasing trend of patients undergoing contralateral prophylactic mastectomy. The Society of Surgical Oncology has provided relative clinical indications for this prophylactic procedure; however, there are other clinical and more important patient factors that are relevant to the decision. In this article, we discuss the indications for this controversial procedure and also explore the patient's motivation to undergo this preventative measure. Nevertheless, the decision to perform a contralateral mastectomy should include a multidisciplinary team approach in conjunction with a patient who has been appropriately informed regarding the risks, benefits and alternatives of this procedure. © 2011 Expert Reviews Ltd. |
| Keywords: | survival; cancer survival; cancer surgery; primary tumor; survival rate; gene mutation; overall survival; histopathology; review; cancer risk; risk benefit analysis; cancer adjuvant therapy; cancer patient; cancer staging; antineoplastic agent; cancer incidence; treatment indication; cancer prevention; chemoprophylaxis; breast cancer; mastectomy; ovariectomy; patient education; motivation; heterozygote; breast reconstruction; cancer mortality; distant metastasis; high risk patient; cancer hormone therapy; tumor suppressor gene; survival time; mammography; family history; anxiety; cancer epidemiology; genetic risk; risk reduction; prophylactic mastectomy; contralateral prophylactic mastectomy; unilateral breast cancer; contralateral mastectomy; risk-reduction surgery |
| Journal Title: | Expert Review of Anticancer Therapy |
| Volume: | 11 |
| Issue: | 8 |
| ISSN: | 1473-7140 |
| Publisher: | Taylor & Francis Group |
| Date Published: | 2011-08-01 |
| Start Page: | 1209 |
| End Page: | 1214 |
| Language: | English |
| DOI: | 10.1586/era.11.100 |
| PROVIDER: | scopus |
| PUBMED: | 21916574 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 3 October 2011" - "CODEN: ERATB" - "Source: Scopus" |
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