Abstract: |
amnesia is a frequently sought property of sedative agents and these drugs are administered in situations where amnesia is highly desirable / however, there is no indicator of an amnesic state, other than retrospective questioning / midazolam, propofol and thiopentone all produce sedation with varying degrees of amnesia / at sedative concentrations, all these agents produce profound EEG effects, primarily consisting of an increase in high-frequency activity over the anterior cortex / describe the relationships between EEG effect, serum concentrations and memory effect in a series of volunteer Ss [22-33 yrs of age] / the beta range of the EEG power spectrum can provide a potentially useful estimation of sedative drug effect on memory as long as both are substantially affected by the drug administered (PsycINFO Database Record (c) 2016 APA, all rights reserved) |