Quantitative comparison of drug-induced amnesic effects: Choice of measures from a verbal learning task Conference Paper
| Authors: | Reinsel, R.; Veselis, R. A.; Dnistrian, A.; Duff, M.; Feshchenko, V. A. |
| Editors: | Bonke, B.; Bovill, J. G.; Moerman, N. |
| Title: | Quantitative comparison of drug-induced amnesic effects: Choice of measures from a verbal learning task |
| Conference Title: | 3rd International Symposium on Memory and Awareness |
| Abstract: | [suggest that] studies of drug-induced amnesia often use verbal-learning tasks, which offer a choice between several measures of memory performance / it is not clear which memory scores are most useful for quantifying drug-induced amnesia / determine empirically the answers to 4 questions / which of the commonly used sedative-hypnotic agents have the most amnesic potential / to what degree is memory impairment a function of serum concentration and sedative effects at the time of learning / can the slope of the function relating memory impairment to drug levels be used as an index of amnesic potency / which of the several available memory scores provides the most sensitive measure of drug-induced amnesia / 39 healthy, consenting volunteers (age range 21 to 45 yr) were randomised in a double-blind fashion to receive [midazolam, propofol, thiopentone or fentanyl with ondansetron pretreatment] (PsycINFO Database Record (c) 2016 APA, all rights reserved) |
| Keywords: | serum concentration & sedative effects & amnesic potential of sedative-hypnotics & memory impairment on verbal-learning task; 21-45 yr olds; implications for sensitivity of memory tests |
| Journal Title | Memory and Awareness in Anaesthesia III |
| Conference Dates: | 1995 Jun |
| Conference Location: | Rotterdam, Netherlands |
| ISBN: | 90-232-3084-1 |
| Publisher: | Van Gorcum & Co |
| Location: | Assen, Netherlands |
| Date Published: | 1996-01-01 |
| Start Page: | 71 |
| End Page: | 83 |
| Language: | English |
| ACCESSION: | 1996-98478-009 |
| PROVIDER: | Ovid Technologies |
| PROVIDER: | psycinfo |
| DOI/URL: | |
| Notes: | Book Chapter: 9 -- Source: PsycINFO |
