Clinical role of breast MRI now and going forward Journal Article
| Authors: | Leithner, D.; Wengert, G. J.; Helbich, T. H.; Thakur, S.; Ochoa-Albiztegui, R. E.; Morris, E. A.; Pinker, K. |
| Article Title: | Clinical role of breast MRI now and going forward |
| Abstract: | Magnetic resonance imaging (MRI) is a well-established method in breast imaging, with manifold clinical applications, including the non-invasive differentiation between benign and malignant breast lesions, preoperative staging, detection of scar versus recurrence, implant assessment, and the evaluation of high-risk patients. At present, dynamic contrast-enhanced MRI is the most sensitive imaging technique for breast cancer diagnosis, and provides excellent morphological and to some extent also functional information. To compensate for the limited functional information, and to increase the specificity of MRI while preserving its sensitivity, additional functional parameters such as diffusion-weighted imaging and apparent diffusion coefficient mapping, and MR spectroscopic imaging have been investigated and implemented into the clinical routine. Several additional MRI parameters to capture breast cancer biology are still under investigation. MRI at high and ultra-high field strength and advances in hard- and software may also further improve this imaging technique. This article will review the current clinical role of breast MRI, including multiparametric MRI and abbreviated protocols, and provide an outlook on the future of this technique. In addition, the predictive and prognostic value of MRI as well as the evolving field of radiogenomics will be discussed. © 2017 The Royal College of Radiologists |
| Keywords: | review; cancer recurrence; cancer patient; cancer staging; nuclear magnetic resonance imaging; breast cancer; high risk patient; preoperative period; dynamic contrast-enhanced magnetic resonance imaging; diffusion weighted imaging; predictive value; apparent diffusion coefficient; cancer prognosis; multiparametric magnetic resonance imaging; human; priority journal; abbreviated magnetic resonance imaging; breast radiotherapy; ultra high magnetic resonance imaging |
| Journal Title: | Clinical Radiology |
| Volume: | 73 |
| Issue: | 8 |
| ISSN: | 0009-9260 |
| Publisher: | W B Saunders Co Ltd |
| Date Published: | 2018-08-01 |
| Start Page: | 700 |
| End Page: | 714 |
| Language: | English |
| DOI: | 10.1016/j.crad.2017.10.021 |
| PROVIDER: | scopus |
| PUBMED: | 29229179 |
| PMCID: | PMC6788454 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 August 2018 -- Source: Scopus |
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