Pruritus associated with targeted anticancer therapies and their management Journal Article


Authors: Wu, J.; Lacouture, M. E.
Article Title: Pruritus associated with targeted anticancer therapies and their management
Abstract: Targeted anticancer therapies have significantly increased the survival of patients with a variety of malignancies, improving tolerability and treatment duration. The increased lifespan and the expanded use of targeted agents have led to a variety of treatment-related adverse events. Pruritus, a common dermatologic adverse event with various incidences ranging from 2.2% to 47% across different categories of targeted anticancer therapies, has been overlooked. This article reviews the incidence, accompanying skin conditions, possible pathomechanism, and proposed management algorithms of pruritus associated with targeted therapies, including immunotherapies. © 2018 Elsevier Inc.
Keywords: pruritus; immunotherapy; targeted therapy; management; itch; cancer
Journal Title: Dermatologic Clinics
Volume: 36
Issue: 3
ISSN: 0733-8635
Publisher: W.B. Saunders Co.  
Date Published: 2018-07-01
Start Page: 315
End Page: 324
Language: English
DOI: 10.1016/j.det.2018.02.010
PROVIDER: scopus
PMCID: PMC6020829
PUBMED: 29929603
DOI/URL:
Notes: Review -- Export Date: 2 July 2018 -- Source: Scopus
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  1. Mario E Lacouture
    457 Lacouture
  2. Jennifer Wu
    8 Wu